Unknown,Transcriptomics,Genomics,Proteomics

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Identification of RVE8 target genes


ABSTRACT: The goal of this study is to identify the targets of RVE8, a MYB-like transcription factor involved in the circadian clock in Arabidopsis. Analysis of 7 days old rve8-1 RVE8::RVE8:GR and rve8-1 seedlings treated with dexamethasone or mock identified genes responsive to RVE8 induction.The RVE8 up-regulated genes are enriched for evening-phased genes while the down-regulated genes are enriched for a morning phase. This study reveals that RVE8 is a master regulator of circadian gene expression in Arabidopsis. Transgenic line rve8-1 RVE8::RVE8:GR and rve8-1 treated with DEX or mock with three biological replicates each, 12 samples in total.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Polly Hsu 

PROVIDER: E-GEOD-38879 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Accurate timekeeping is controlled by a cycling activator in Arabidopsis.

Hsu Polly Yingshan PY   Devisetty Upendra K UK   Harmer Stacey L SL  

eLife 20130430


Transcriptional feedback loops are key to circadian clock function in many organisms. Current models of the Arabidopsis circadian network consist of several coupled feedback loops composed almost exclusively of transcriptional repressors. Indeed, a central regulatory mechanism is the repression of evening-phased clock genes via the binding of morning-phased Myb-like repressors to evening element (EE) promoter motifs. We now demonstrate that a related Myb-like protein, REVEILLE8 (RVE8), is a dire  ...[more]

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