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Gene Expression Changes Associated With TLR2 Mediated Inhibition of Allergen Specific TH2 Response In Vitro

ABSTRACT: Investigation of the gene expression changes associated with TLR2 adjuvant (lipoteichoic acid; LTA) inhibition of allergic TH2 responses in peripheral blood mononuclear cell cultures (derived from house dust mite allergic individuals) stimulated with house dust mite extract. Pooled samples from 5 individuals were analysed by microarray; qPCR validation was carried out in a larger cohort of 23 individuals.

ORGANISM(S): Homo sapiens

SUBMITTER: Antonia Pritchard

PROVIDER: E-GEOD-39476 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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