Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

C.elegans exposed to P. aeurigonsa: Colonized vs Non colonized animals

ABSTRACT: Transcriptional profiling of adult C.elegans exposed to E.coli or to GFP-expressing P. aeruginosa (strain PA14). For P. aeruginosa exposure, worms were separated into 2 groups - fully colonized (green) or non-colonized (dark). Three conditions (E.coli, P. aeurginosa colonized, and P. aeurginosa non-colonized). 2-color arrrays, each sample co-hybridized with the same reference RNA sample from mixed stage C.elegans cultures Each condition includes 3 biological replicates - 2 using the wormsorter (WS) to separate colonized from non-colonized and one hand picked (HP) under a fluorescent stereoscope

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Michael Shapira 

PROVIDER: E-GEOD-39536 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Dissociation of immune responses from pathogen colonization supports pattern recognition in C. elegans.

Twumasi-Boateng Kwame K   Shapira Michael M  

PloS one 20120413 4

Caenorhabditis elegans has been used for over a decade to characterize signaling cascades controlling innate immune responses. However, what initiates these responses in the worm has remained elusive. To gain a better understanding of the initiating events we delineated genome-wide immune responses to the bacterial pathogen Pseudomonas aeruginosa in worms heavily-colonized by the pathogen versus worms visibly not colonized. We found that infection responses in both groups were identical, suggest  ...[more]

Similar Datasets

Transcriptomics C.elegans treated with control or elt-2 RNAi during adulthood and exposed to E. coli or P. aeruginosa
2014-12-04 | E-GEOD-63846 | biostudies-arrayexpress
Transcriptomics C.elegans exposed to P. aeurigonsa: Colonized vs Non colonized animals
2012-07-20 | GSE39536 | GEO
Transcriptomics C.elegans treated with control or elt-2 RNAi during adulthood and exposed to E. coli or P. aeruginosa
2014-12-04 | GSE63846 | GEO
Genomics Rice roots: Non-colonized (sterile) control vs. colonized with Azoarcus olearius BH72
| PRJNA563164 | ENA
Genomics Caenorhabditis elegans
| PRJNA171058 | ENA
Genomics Small RNA and degradome sequencing in Medicago truncatula roots (Glomus intraradices colonized and non-colonized)
| PRJNA134973 | ENA
Other Gene expression in the small intestine of mice colonized with Pseudomonas aeruginosa
2019-02-01 | GSE125983 | GEO
Other Mono-Colonized GF Reporter Mice
2021-08-31 | MSV000088040 | MassIVE
Transcriptomics Gene expression patterns in the head horns, thoracic horns, and legs of the horned beetles Onthophagus taurus
2010-05-18 | E-GEOD-13616 | biostudies-arrayexpress
Transcriptomics Transcriptional profiling of mouse ileum in response to colonization with a zebrafish or mouse gut microbiota
2006-07-07 | GSE5198 | GEO