Hypoxia induces myocardial regeneration in zebrafish
Ontology highlight
ABSTRACT:
ORGANISM(S): Danio rerio
SUBMITTER: Chris Jopling
PROVIDER: E-GEOD-39842 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Hypoxia induces myocardial regeneration in zebrafish.
Jopling Chris C Suñé Guillermo G Faucherre Adèle A Fabregat Carme C Izpisua Belmonte Juan Carlos JC
Circulation 20121114 25
<h4>Background</h4>Hypoxia plays an important role in many biological/pathological processes. In particular, hypoxia is associated with cardiac ischemia. which, although initially inducing a protective response, will ultimately lead to the death of cardiomyocytes and loss of tissue, severely affecting cardiac functionality. Although myocardial damage/loss remains an insurmountable problem for adult mammals, the same is not true for adult zebrafish, which are able to completely regenerate their h ...[more]
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