Chronic Helicobacter pylori Infection with Sydney Strain 1 and Mouse-Adapted Sydney Strain 2000
Ontology highlight
ABSTRACT:
ORGANISM(S): Helicobacter pylori
SUBMITTER: Lucinda Thompson
PROVIDER: E-GEOD-3988 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Chronic Helicobacter pylori infection with Sydney strain 1 and a newly identified mouse-adapted strain (Sydney strain 2000) in C57BL/6 and BALB/c mice.
Thompson Lucinda J LJ Danon Stephen J SJ Wilson John E JE O'Rourke Jani L JL Salama Nina R NR Falkow Stanley S Mitchell Hazel H Lee Adrian A
Infection and immunity 20040801 8
The mouse model of Helicobacter pylori-induced disease using Sydney strain 1 (SS1) has been used extensively in Helicobacter research. Herein we describe the isolation and characterization of a new mouse-colonizing strain for use in comparative studies. One strain capable of persistent mouse colonization was isolated from a total of 110 clinical isolates and is named here SS2000 (Sydney strain 2000). Genome typing revealed a number of differences between SS1 and SS2000 as well as between them an ...[more]
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