Unknown,Transcriptomics,Genomics,Proteomics

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Whole Genome sequencing of a normal karyotype AML cell line


ABSTRACT: Normal Karyotype acute myeloid leukemia (NK-AML) represents approximately 50% of all cases of AML which patients develop. Most AML cell lines are highly abnormal and therefore not good models for investigating NK-AML biology a novel AML cell line, CG-SH, was recently estabished and here we characterize the gene expression and mutations present through high-throughput sequencing of RNA and genomic DNA using a HiSeq 2000 The overall design of the experiment was to characterize, at single base pair resolution, all of the genetic defects present in a novel normal karyotype cell line, CG-SH

ORGANISM(S): Homo sapiens

SUBMITTER: Brian Wilhelm 

PROVIDER: E-GEOD-40199 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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