Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Olaf Thuerigen
PROVIDER: E-GEOD-4056 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Thuerigen Olaf O Schneeweiss Andreas A Toedt Grischa G Warnat Patrick P Hahn Meinhard M Kramer Heidi H Brors Benedikt B Rudlowski Christian C Benner Axel A Schuetz Florian F Tews Bjoern B Eils Roland R Sinn Hans-Peter HP Sohn Christof C Lichter Peter P
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060401 12
<h4>Purpose</h4>Primary systemic therapy (PST) with gemcitabine (G), epirubicin (E), and docetaxel (Doc) has resulted in a pathologic complete response (pCR) in 26% of primary breast cancer patients. This study was aimed at the identification of a gene expression signature in diagnostic core biopsy tissue samples that predicts pCR.<h4>Patients and methods</h4>Core biopsy samples from patients with operable primary breast cancer, T2-4N0-2M0, enrolled onto two phase I and II trials evaluating GEDo ...[more]