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Genome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE34902: Genome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus [Affymetrix] GSE34927: Genome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus [ChIP-Seq] Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Cory Rubel

PROVIDER: E-GEOD-40663 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Research resource: Genome-wide profiling of progesterone receptor binding in the mouse uterus.

Rubel Cory A CA Lanz Rainer B RB Kommagani Ramakrishna R Franco Heather L HL Lydon John P JP DeMayo Francesco J FJ

Molecular endocrinology (Baltimore, Md.) 20120525 8

Progesterone (P4) signaling through its nuclear transcription factor, the progesterone receptor (PR), is essential for normal uterine function. Although deregulation of PR-mediated signaling is known to underscore uterine dysfunction and a number of endometrial pathologies, the early molecular mechanisms of this deregulation are unclear. To address this issue, we have defined the genome-wide PR cistrome in the murine uterus using chromatin immunoprecipitation (ChIP) followed by massively paralle ...[more]

PMID: 22638070

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Genome-wide Profiling of Progesterone Receptor and GATA2 Binding in the Mouse Uterus [ChIP-Seq]

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