Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: didier wion
PROVIDER: E-GEOD-41184 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nissou Marie-France MF Brocard Jacques J El Atifi Michèle M Guttin Audrey A Andrieux Annie A Berger François F Issartel Jean-Paul JP Wion Didier D
Journal of Alzheimer's disease : JAD 20130101 3
Seasonal or chronic vitamin D deficiency and/or insufficiency is highly prevalent in the human population. Receptors for 1,25-dihydroxyvitamin D3, the hormonal metabolite of vitamin D, are found throughout the brain. To provide further information on the role of this hormone on brain function, we analyzed the transcriptomic profiles of mixed neuron-glial cell cultures in response to 1,25-dihydroxyvitamin D3. 1,25-dihydroxyvitamin D3 treatment increases the mRNA levels of 27 genes by at least 1.9 ...[more]