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Integrated analysis of transcript level regulation of metabolism during human adipocyte differentiation

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Merja Heinäniemi

PROVIDER: E-GEOD-41578 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network.

Galhardo Mafalda M Sinkkonen Lasse L Berninger Philipp P Lin Jake J Sauter Thomas T Heinäniemi Merja M

Nucleic acids research 20131105 3

Metabolic diseases and comorbidities represent an ever-growing epidemic where multiple cell types impact tissue homeostasis. Here, the link between the metabolic and gene regulatory networks was studied through experimental and computational analysis. Integrating gene regulation data with a human metabolic network prompted the establishment of an open-sourced web portal, IDARE (Integrated Data Nodes of Regulation), for visualizing various gene-related data in context of metabolic pathways. Motiv ...[more]

PMID: 24198249

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