Comparison of Gene Expression in Psoriatic Skin from Different Sources
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Jeannette Bigler
PROVIDER: E-GEOD-41664 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Cross-study homogeneity of psoriasis gene expression in skin across a large expression range.
Bigler Jeannette J Rand Hugh A HA Kerkof Keith K Timour Martin M Russell Christopher B CB
PloS one 20130104 1
<h4>Background</h4>In psoriasis, only limited overlap between sets of genes identified as differentially expressed (psoriatic lesional vs. psoriatic non-lesional) was found using statistical and fold-change cut-offs. To provide a framework for utilizing prior psoriasis data sets we sought to understand the consistency of those sets.<h4>Methodology/principal findings</h4>Microarray expression profiling and qRT-PCR were used to characterize gene expression in PP and PN skin from psoriasis patients ...[more]
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