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Longitudinal expression profiling in whole blood of multiple sclerosis patients and controls

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Dorothee Nickles

PROVIDER: E-GEOD-41850 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls.

Nickles Dorothee D Chen Hsuan P HP Li Michael M MM Khankhanian Pouya P Madireddy Lohith L Caillier Stacy J SJ Santaniello Adam A Cree Bruce A C BA Pelletier Daniel D Hauser Stephen L SL Oksenberg Jorge R JR Baranzini Sergio E SE

Human molecular genetics 20130606 20

Multiple sclerosis (MS) is the most common autoimmune disease of the central nervous system (CNS). It is characterized by the infiltration of autoreactive immune cells into the CNS, which target the myelin sheath, leading to the loss of neuronal function. Although it is accepted that MS is a multifactorial disorder with both genetic and environmental factors influencing its development and course, the molecular pathogenesis of MS has not yet been fully elucidated. Here, we studied the longitudin ...[more]

PMID: 23748426

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longitudinal expression profiling in whole blood of multiple sclerosis patients and controls [IFN_replication dataset]

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