Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: olivier Terrier
PROVIDER: E-GEOD-42003 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a.
Terrier Olivier O Textoris Julien J Carron Coralie C Marcel Virginie V Bourdon Jean-Christophe JC Rosa-Calatrava Manuel M
The Journal of general virology 20130123 Pt 5
While post-transcriptional regulation of gene expression by microRNAs (miRNAs) has been shown to be involved in influenza virus replication cycle, only a few studies have further investigated this aspect in a human cellular model infected with human influenza viruses. In this study, we performed miRNA global profiling in human lung epithelial cells (A549) infected by two different subtypes of human influenza A viruses (H1N1 and H3N2). We identified a common miRNA signature in response to infecti ...[more]
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