Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Lang Lei
PROVIDER: E-GEOD-42061 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lei Lang L Li Houxuan H Yan Fuhua F Xiao Yin Y
PloS one 20130816 8
A finely-tuned innate immune response plays a pivotal role in protecting host against bacterial invasion during periodontal disease progression. Hyperlipidemia has been suggested to exacerbate periodontal health condition. However, the underlying mechanism has not been addressed. In the present study, we investigated the effect of hyperlipidemia on innate immune responses to periodontal pathogen Porphyromonas gingivalis infection. Apolipoprotein E-deficient and wild-type mice at the age of 20 we ...[more]