Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: J. Scott Butler
PROVIDER: E-GEOD-42231 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Schmidt Karyn K Xu Zhenjiang Z Mathews David H DH Butler J Scott JS
RNA (New York, N.Y.) 20120824 10
RNA surveillance systems function at critical steps during the formation and function of RNA molecules in all organisms. The RNA exosome plays a central role in RNA surveillance by processing and degrading RNA molecules in the nucleus and cytoplasm of eukaryotic cells. The exosome functions as a complex of proteins composed of a nine-member core and two ribonucleases. The identity of the molecular determinants of exosome RNA substrate specificity remains an important unsolved aspect of RNA surve ...[more]