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Transcription profiling of mouse macrophage cell line Polysomal, free mRNP, and total cellular mRNA of before and after LPS stimulation

ABSTRACT: Bacterial lipopolysaccharide(LPS) dramatically activates macrophages. So far, dozen of papers indicated that many proinflammatory molecules are transcriptionaly regulated during response. Despite of this,translational regulation is not fully elucidated especially in a comprehensive fashion. In this series, we investigated expression profiles of translation active (polysome) inactive (free mRNP) mRNAs of a typical mouse macrophage cell line, J774.1. Moreover, we also measured total cellular RNA level as a reference. Experiment Overall Design: Triplicates for each time points are included.

ORGANISM(S): Mus musculus

SUBMITTER: Hiroshi Kitamura

PROVIDER: E-GEOD-4288 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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