Transcription profiling of human airway epithelial cells in asthmatics, smokers and healthy controls

ABSTRACT: We collected airway epithelial brushings for microarray analysis from 42 asthmatics and two control groups – 28 healthy subjects and 16 smokers. A subgroup of 32 asthmatics completed a randomized placebo-controlled trial of fluticasone propionate in which collection of brushings was repeated after 1 week of treatment. Experiment Overall Design: 1) Comparison of gene expression in asthmatics to healthy controls Experiment Overall Design: 2) Comparison of smokers to healthy controls Experiment Overall Design: 3) Comparison of change in gene expression in the fluticasone treated group to the change in the placebo treated group

ORGANISM(S): Homo sapiens

SUBMITTER: Prescott Gurney Woodruff 

PROVIDER: E-GEOD-4302 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress