Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Canonical Nlrp3 inflammasome activation links systemic age-related inflammation with functional decline


ABSTRACT: This experiment was performed to analyze the contribution of NLRP3 inflammasome activation to age-related changes in hippocampal RNA. The hypothesis was that decreased inflammasome activation would reduce hippocampal inflammation. Results indicate that inflammasome knockout animals are protected from age-related changes in hippocampal gene expression Gene expression profiles of young (1 month) and old (21-23 month) wild type, CIAS -/- and ASC -/- mouse hippocampal tissue were compared. Total mRNA was extracted using Trizol.

ORGANISM(S): Mus musculus

SUBMITTER: Ryan Grant 

PROVIDER: E-GEOD-43034 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2013-09-05 | GSE43034 | GEO
2014-07-01 | E-GEOD-58959 | biostudies-arrayexpress
2024-07-25 | PXD054126 | Pride
2022-03-09 | GSE197606 | GEO
2021-11-16 | GSE188767 | GEO
2023-05-29 | GSE233641 | GEO
| PRJNA978574 | ENA
2014-07-01 | GSE58959 | GEO
2016-08-11 | E-GEOD-77611 | biostudies-arrayexpress
2022-05-19 | PXD028582 | Pride