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Gain and loss of H4K16 acetylation during ES cell differentiation [NimbleGen ChIP-chip]

ABSTRACT: H4K16ac is gained on hox loci and lost on pluripotency genes upon differentiation ChIP on chip over hox loxi and pluripotency genes for H4K16ac in undifferentiated ES cells and after 3 days of retinoic acid treatment

ORGANISM(S): Mus musculus

SUBMITTER: Gillian Taylor

PROVIDER: E-GEOD-43099 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction (I) [ChIP-Seq]

Project description:We report that acetylation of H4K16 is a new marker of active enhancers and that some enhancers are marked by H3K4me1, MOF and H4K16ac but not by acetylated H3K27 or p300, suggesting that they are novel p300-independent regulatory elements. ChIP-seq for H4K16 acetylation in undifferentiated ES cells, and cells after 3 days of retinoic acid differentiation, along with MNase digested input for both samples

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H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction [NimbleGen array]

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A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naïve pluripotency in mouse embryonic stem cells

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Gain and loss of H4K16 acetylation during ES cell differentiation [NimbleGen ChIP-chip]

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Epigenetic profiling of histone H3K4me1, H3K4me3, H3K27me3, H3ac, H4ac, CBP and P300 using ChIP-chip

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Mapping of ETV1 genomic binding sites in gastrointestinal stromal tumor (GIST).

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The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

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