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Phenotypic changes in PMN in Periodontits patients

ABSTRACT: The goal of this study is to use a rapid method for oral neutrophil isolation and use a transcriptomics approach to characterize and compare the neutrophil gene expression profile in the blood and oral compartment of healthy individuals, chronic periodontitis patients and refractory periodontitis patients. Total RNA obtained from isolated neutrophils from blood and oral samples of Healthy patients, chronic periodontits patients and refractory periodontitis patients

ORGANISM(S): Homo sapiens

SUBMITTER: Flavia Lakschevitz

PROVIDER: E-GEOD-43525 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Phenotypic changes in PMN in Periodontits patients

Project description:The goal of this study is to use a rapid method for oral neutrophil isolation and use a transcriptomics approach to characterize and compare the neutrophil gene expression profile in the blood and oral compartment of healthy individuals, chronic periodontitis patients and refractory periodontitis patients.

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peripheral blood mononuclear cells (PBMCs) of pre- and post-treatment periodontitis patients and healthy donors by single-cell RNA profiling

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Periodontitis is associated with a type-1 interferon signature in peripheral blood neutrophils

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