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Expression data of GMP and MDP from wild-type and Trib1-/- mice

ABSTRACT: Trib1 is critical for some myeloid cell differentiation. Therefore we used microarrays to investigate gene expression profiles in wild-type and Trib1-/- progenitor of myeloid cells. Progenitor cells, such as GMP and MDP, obtained from wild-type and Trib1-/- mice were sorted, followed by RNA extraction. Then hybridization on affymetrix microarrays was performed.

ORGANISM(S): Mus musculus

SUBMITTER: Takashi Satoh

PROVIDER: E-GEOD-43563 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression data of GMP and MDP from wild-type and Trib1-/- mice

Project description:Trib1 is critical for some myeloid cell differentiation. Therefore we used microarrays to investigate gene expression profiles in wild-type and Trib1-/- progenitor of myeloid cells.

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Murine GMP- and MDP-derived classical monocytes have distinct functions and fates [dataset 1]

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The chromatin structures of GMP-MoPs are shifted toward ones that favors an aberrant differentiation pathway generating GMP-MoPs from proNeu1 [ATAC-seq]

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Trib1 promotes acute myeloid leukemia progression by modulating transcriptional programs of Hoxa9 [array]

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