Unknown,Transcriptomics,Genomics,Proteomics

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Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons


ABSTRACT: Here we reveal a hierarchical mechanism in the direct conversion of fibroblasts into induced neuronal (iN) cells mediated by the transcription factors Ascl1, Brn2, and Myt1l. Examination of global transcriptional changes and mapping genome-wide transcription factors occupancy at distinct time points during the transdifferentiation process

ORGANISM(S): Mus musculus

SUBMITTER: Kun Qu 

PROVIDER: E-GEOD-43916 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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