Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Humam Kadara
PROVIDER: E-GEOD-44077 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Journal of the National Cancer Institute 20140222 3
<h4>Background</h4>Earlier work identified specific tumor-promoting abnormalities that are shared between lung cancers and adjacent normal bronchial epithelia. We sought to characterize the yet unknown global molecular and adjacent airway field cancerization (FC) in early-stage non-small cell lung cancer (NSCLC).<h4>Methods</h4>Whole-transcriptome expression profiling of resected early-stage (I-IIIA) NSCLC specimens (n = 20) with matched tumors, multiple cytologically controlled normal airways w ...[more]