Circulating miRNAs as novel marker of pulmonary hypertension
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Sandeep Kumar
PROVIDER: E-GEOD-44145 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Circulating miRNAs as potential marker for pulmonary hypertension.
Wei Chuanyu C Henderson Heather H Spradley Christopher C Li Li L Kim Il-Kwon IK Kumar Sandeep S Hong Nayeon N Arroliga Alejandro C AC Gupta Sudhiranjan S
PloS one 20130523 5
MircoRNAs (miRNAs) are small non-coding RNAs that govern the gene expression and, play significant role in the pathogenesis of heart failure. The detection of miRNAs in circulation of pulmonary hypertensive (PH) human subjects remains elusive. In the current study, we determined the pattern of miRNAs of mild-to-severe human PH subjects and, compared them with the control subjects by miRNA array. Blood was obtained using fluoroscopic and waveform guided catheterization from the distal (pulmonary ...[more]
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