Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Shobbir Hussain
PROVIDER: E-GEOD-44384 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Cell reports 20130718 2
Autosomal-recessive loss of the NSUN2 gene has been identified as a causative link to intellectual disability disorders in humans. NSun2 is an RNA methyltransferase modifying cytosine-5 in transfer RNAs (tRNAs), yet the identification of cytosine methylation in other RNA species has been hampered by the lack of sensitive and reliable molecular techniques. Here, we describe miCLIP as an additional approach for identifying RNA methylation sites in transcriptomes. miCLIP is a customized version of ...[more]