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Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptomics profilling of B. anthracis grown under different environmental perturbation

ABSTRACT: The effect of factors that affect toxin production i.e. glucose, bicarbonate and growth temperature was investigated by transcriptional profilling using microarrays. Sequential environmental perturbations were carried out in R media, wherein glucose was replaced by glycerol (0.25%) [referred as 'R(-)Glucose'] or no bicarbonate [referred as 'R(-)Bicarbonate'] was added or the growth temperature was 28M-BM-0C instead of 37M-BM-0C [referred as 'R-28C']. The strain was grown in a chemically defined media called R medium in the presence of 5%CO2 at 37M-BM-0C to simulate host like conditions and induce toxin production (referred as M-bM-^@M-^XR-FullM-bM-^@M-^Y), which is used as control in this study.

ORGANISM(S): Bacillus anthracis

SUBMITTER: Gurudutta Panda

PROVIDER: E-GEOD-44432 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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