Androgen receptor-coregulators hormone responsiveness LNCaP / GSF

ABSTRACT: The text description is: LNCaP are androgen receptor expressing prostate carcinoma cells. Genital skin fibroblasts also express the androgen receptor. Cells were either proliferating or they were G0-arrested. Treatment of cells was performed with either the androgen DHT (dihydrotestosterone), the androgen analogue R1881 (methyltrienolone), or the solvent ethanol. Some hybridizations were performed in the type 1 design. In these cases, the hormone treated sample was hybridized against the ethanol treated sample on the same microarray. Hormone mediated induction or repression of gene transcription can directly be deduced from R/G normalized ratios on arrays. For other experiments, the ethanol treated control and the hormone treated experiment were hybridized on separate microarrays against a

ORGANISM(S): Homo sapiens

SUBMITTER: Samuel DePrimo 

PROVIDER: E-GEOD-4454 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress