Ontology highlight
ABSTRACT:
ORGANISM(S): Caenorhabditis elegans
SUBMITTER: Jiaofang Shao
PROVIDER: E-GEOD-44710 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Shao Jiaofang J He Kan K Wang Hao H Ho Wing Sze WS Ren Xiaoliang X An Xiaomeng X Wong Ming Kin MK Yan Bin B Xie Dongying D Stamatoyannopoulos John J Zhao Zhongying Z
The Journal of biological chemistry 20131006 46
Cell fate specification is typically initiated by a master regulator, which is relayed by tissue-specific regulatory proteins (usually transcription factors) for further enforcement of cell identities, but how the factors are coordinated among each other to "finish up" the specification remains poorly understood. Caenorhabditis elegans epidermis specification is initiated by a master regulator, ELT-1, that activates its targets, NHR-25 and ELT-3, two epidermis-specific transcription factors that ...[more]