Unknown,Transcriptomics,Genomics,Proteomics

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NA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus.


ABSTRACT: Sea cucumbers (Holothuroidea; Echinodermata) have the capacity to regenerate lost tissues and organs.We used RNA-Seq to determine gene expression profiles associated with intestinal regeneration in A. japonicus at 3, 7, 14 and 21 days post evisceration (dpe) At least 15 individuals per stage, at 3, 7, 14 and 21 days post evisceration (dpe) were used for our experiments.

ORGANISM(S): Apostichopus japonicus

SUBMITTER: Lina Sun 

PROVIDER: E-GEOD-44995 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

RNA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus. [corrected].

Sun Lina L   Yang Hongsheng H   Chen Muyan M   Ma Deyou D   Lin Chenggang C  

PloS one 20130806 8


<h4>Background</h4>Sea cucumbers (Holothuroidea; Echinodermata) have the capacity to regenerate lost tissues and organs. Although the histological and cytological aspects of intestine regeneration have been extensively studied, little is known of the genetic mechanisms involved. There has, however, been a renewed effort to develop a database of Expressed Sequence Tags (ESTs) in Apostichopus japonicus, an economically-important species that occurs in China. This is important for studies on geneti  ...[more]

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