MiRNAs regulation by miR-145 in pancreatic cancer

ABSTRACT: miR-145 is a tumor suppressor miRNA in various malignancies including pancreatic cancer. How miR-145 regulates expression of other miRNAs could provide a panoramic view of the development of pancreatic cancer. Therefore, in this project, we aimed to characterize how other miRNAs are affected by miR-145 in hope for understanding proteomic changes that are not explained by miR-145 alone. miRNA microarray was used to compare expression of all miRNAs 48 hr after transfection of miR-145 mimics or control scramble RNA in a pancreatic cancer cell line, Mia-PaCa2.

ORGANISM(S): Homo sapiens

SUBMITTER: Tai-Chung Huang 

PROVIDER: E-GEOD-45246 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress