Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yujuan Dong
PROVIDER: E-GEOD-45349 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Dong Yujuan Y Zhao Junhong J Wu Chung-Wah CW Zhang Lijing L Liu Xiaodong X Kang Wei W Leung Wing-Wah WW Zhang Ning N Chan Francis K L FK Sung Joseph J Y JJ Ng Simon S M SS Yu Jun J
Molecular cancer research : MCR 20130530 9
<h4>Unlabelled</h4>Dysregulated microRNA (miRNA) expression was profiled through a miRNA array comparison between human colorectal cancer tumors and their adjacent normal tissues. Specifically, using laser capture micro-dissection, miR-133a was shown to be significantly downregulated in primary colorectal cancer specimens compared with matched adjacent normal tissue. Ectopic expression of miR-133a significantly suppressed colorectal cancer cell growth in vitro and in vivo. Cell-cycle analysis re ...[more]