Unknown,Transcriptomics,Genomics,Proteomics

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MicroRNA expression profile of breast cancer patients with adjacent normal control group.


ABSTRACT: To discriminate miRNA expression differences between adjacent normal and tumor tissues of breast cancer. 101 breast tumor + 15 adjacent breast normal tissue samples.

ORGANISM(S): Homo sapiens

SUBMITTER: Chia-Hsien Lee 

PROVIDER: E-GEOD-45666 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

MicroRNA-regulated protein-protein interaction networks and their functions in breast cancer.

Lee Chia-Hsien CH   Kuo Wen-Hong WH   Lin Chen-Ching CC   Oyang Yen-Jen YJ   Huang Hsuan-Cheng HC   Juan Hsueh-Fen HF  

International journal of molecular sciences 20130530 6


MicroRNAs, which are small endogenous RNA regulators, have been associated with various types of cancer. Breast cancer is a major health threat for women worldwide. Many miRNAs were reported to be associated with the progression and carcinogenesis of breast cancer. In this study, we aimed to discover novel breast cancer-related miRNAs and to elucidate their functions. First, we identified confident miRNA-target pairs by combining data from miRNA target prediction databases and expression profile  ...[more]

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