Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Mark Magbanua
PROVIDER: E-GEOD-46068 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Magbanua Mark Jesus M MJ Melisko Michelle M Roy Ritu R Sosa Eduardo V EV Hauranieh Louai L Kablanian Andrea A Eisenbud Lauren E LE Ryazantsev Artem A Au Alfred A Scott Janet H JH Park John W JW
Cancer research 20131018 23
Although leptomeningeal carcinomatosis is a well-established clinical syndrome, virtually nothing is known about the tumor cells responsible for this particularly aggressive metastatic process. To isolate cerebrospinal fluid-derived tumor cells (CSFTC) from 15 patients with metastatic breast cancer diagnosed with leptomeningeal carcinomatosis, CSF samples were subjected to a two-step method involving immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS), a technique previou ...[more]