Unknown,Transcriptomics,Genomics,Proteomics

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The acute transcriptional response of the coral Acropora millepora to immune challenge: expression of GiMAP/IAN genes links the innate immune response of corals with those of mammals and plants


ABSTRACT: This studies investigates the acute response of the coral Acropora millepora to two immunogenes: MDP (bacterial mimic) and pIC (viral mimic). Three members of the GiMAP familly were found to respond strongly to MDP treatment, showing analalogy to the immune response in vertebrates and plants. Differential gene expression following treatment with two immunogenes

ORGANISM(S): Acropora millepora

SUBMITTER: Sylvain Foret 

PROVIDER: E-GEOD-46389 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The acute transcriptional response of the coral Acropora millepora to immune challenge: expression of GiMAP/IAN genes links the innate immune responses of corals with those of mammals and plants.

Weiss Yvonne Y   Forêt Sylvain S   Hayward David C DC   Ainsworth Tracy T   King Rob R   Ball Eldon E EE   Miller David J DJ  

BMC genomics 20130614


<h4>Background</h4>As a step towards understanding coral immunity we present the first whole transcriptome analysis of the acute responses of Acropora millepora to challenge with the bacterial cell wall derivative MDP and the viral mimic poly I:C, defined immunogens provoking distinct but well characterised responses in higher animals.<h4>Results</h4>These experiments reveal similarities with the responses both of arthropods and mammals, as well as coral-specific effects. The most surprising fin  ...[more]

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