Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Arnaud Boulling
PROVIDER: E-GEOD-47002 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Boulling Arnaud A Wicht Linda L Schorderet Daniel F DF
Molecular vision 20130806
<h4>Purpose</h4>A homozygous mutation in the H6 family homeobox 1 (HMX1) gene is responsible for a new oculoauricular defect leading to eye and auricular developmental abnormalities as well as early retinal degeneration (MIM 612109). However, the HMX1 pathway remains poorly understood, and in the first approach to better understand the pathway's function, we sought to identify the target genes.<h4>Methods</h4>We developed a predictive promoter model (PPM) approach using a comparative transcripto ...[more]