Ontology highlight
ABSTRACT:
ORGANISM(S): Danio rerio
SUBMITTER: Richard Beyer
PROVIDER: E-GEOD-47039 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Tilton Fred A FA Tilton Susan C SC Bammler Theo K TK Beyer Richard P RP Stapleton Patricia L PL Scholz Nathaniel L NL Gallagher Evan P EP
Aquatic toxicology (Amsterdam, Netherlands) 20110202 3-4
Chemical exposures in fish have been linked to loss of olfaction leading to an inability to detect predators and prey and decreased survival. However, the mechanisms underlying olfactory neurotoxicity are not well characterized, especially in environmental exposures which involve chemical mixtures. We used zebrafish to characterize olfactory transcriptional responses by two model olfactory inhibitors, the pesticide chlorpyrifos (CPF) and mixtures of CPF with the neurotoxic metal copper (Cu). Mic ...[more]