Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

The genetic basis for differential macrophage activation


ABSTRACT: Differential macrophage activation mediate genetic differences to a variety of inflammatory pathologies. We wanted to elucidate the transcriptional and regulatory programs regulating differential macrophage activation in genetically diverse mouse strains. Bone marrow-derived macrophages (BMDMs) from AJ and C57BL/6j mice were left unstimulated, stimulated with IFN/TNF, or IL-4, or CpG, or LPS or IFN/TNF and infected with a type II (Pru A7) strain of Toxoplasma gondii, or infected with Pru A7 and gene expression analyzed 18 hrs later.

ORGANISM(S): Mus musculus

SUBMITTER: Musa Hassan 

PROVIDER: E-GEOD-47046 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2013-03-20 | E-GEOD-45309 | biostudies-arrayexpress
2013-11-13 | E-GEOD-47540 | biostudies-arrayexpress
2022-01-07 | PXD028667 | Pride
2015-02-02 | E-GEOD-65436 | biostudies-arrayexpress
2014-01-14 | E-GEOD-53810 | biostudies-arrayexpress
2013-02-19 | E-GEOD-34913 | biostudies-arrayexpress
2015-09-07 | E-GEOD-61055 | biostudies-arrayexpress
2010-10-01 | E-GEOD-21895 | biostudies-arrayexpress
2021-03-24 | GSE168710 | GEO
2011-03-01 | E-GEOD-27112 | biostudies-arrayexpress