Circulating microRNAs predict biochemical recurrence in prostate cancer patients
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Luke Selth
PROVIDER: E-GEOD-47125 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Circulating microRNAs predict biochemical recurrence in prostate cancer patients.
Selth L A LA Townley S L SL Bert A G AG Stricker P D PD Sutherland P D PD Horvath L G LG Goodall G J GJ Butler L M LM Tilley W D WD
British journal of cancer 20130711 3
<h4>Background</h4>Circulating microRNAs (miRNAs) are emerging as promising biomarkers for prostate cancer. Here, we investigated the potential of these molecules to assist in prognosis and treatment decision-making.<h4>Methods</h4>MicroRNAs in the serum of patients who had experienced rapid biochemical recurrence (BCR) (n=8) or no recurrence (n=8) following radical prostatectomy (RP) were profiled using high-throughput qRT-PCR. Recurrence-associated miRNAs were subsequently quantitated by qRT-P ...[more]
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