Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Sara Arab
PROVIDER: E-GEOD-4725 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
American journal of physiology. Heart and circulatory physiology 20071130 2
The purpose of this study was to determine if hypoxia elicits different proliferative and apoptotic responses in systemic arterial smooth muscle cells incubated under conditions that do or do not result in cellular ATP depletion and whether these effects are relevant to vascular remodeling in vivo. Gene expression profiling was used to identify potential regulatory pathways. In human aortic smooth muscle cells (HASMCs) incubated at 3% O(2), proliferation and progression through the G1/S interpha ...[more]