Subventricular zone progenitors healthy vs. Experimental Autoimmune Encephalomyelitis mice

ABSTRACT: Transcriptional profiling of subventricular zone (SVZ) progenitors comparing control healthy mice to mice induced to develop an autoimmune demyelination (EAE model). Goal was to unveil genes involved in demyelination-induced reactivity of SVZ progenitors. Two-condition experiment, healthy vs. EAE derived SVZ progenitors. Biological replicates: 2 control replicates, 2 EAE replicates. SVZ progenitors were sorted in two cell populations: neuronal progenitors (PSA-NCAM magnetic sorting) and glial progenitors (NG2 magnetic sorting). Progenitors from healthy mice are reference samples.

ORGANISM(S): Mus musculus

SUBMITTER: Myriam CAYRE 

PROVIDER: E-GEOD-47486 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress