Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of lungs from HeJ (TLR4 mutant) and OuJ (wild type) mice that have been exposed to ozone to study the molecular mechanisms underlying the effect of ozone on airways hyperpermability


ABSTRACT: Ozone is a very common environmental pollutant and has been associated with the exacerbation of cardiopulmonary diseases like asthma. In this study the molecular mechanisms underlying the effect of ozone on airways hyperpermability were investigated. Two strains of mice, HeJ (Tlr4 mutant) and OuJ (wildtype) were exposed continuously to air or 0.3ppm of ozone. Lungs were removed and RNA was collected to generate expression profiles.

ORGANISM(S): Mus musculus

SUBMITTER: Eric Hoffman 

PROVIDER: E-GEOD-476 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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