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Genome-wide analysis of berberine chloride-responsive gene expression in HepG2 liver cell line

ABSTRACT: Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects. Here, we used gene expression microarray to analyze gene expression profiles of HepG2 human hepatoma cell line after berberine chloride treatment or 0.08% DMSO as control. Comparing gene expression profiles of 40 M-BM-5M-BM--M berberine-treated HepG2 human hepatoma cell line to those of control cells sampled after 4 hours treatment. A 50 mM stock solution of Berberine chloride was prepared in DMSO. Cells were treated with 40 M-BM-5M-BM--M berberine chloride or 0.08% DMSO as control.

ORGANISM(S): Homo sapiens

SUBMITTER: Ting-fang Lo

PROVIDER: E-GEOD-47786 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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