Cyclin D1 determines estrogen depependent signaling in mouse mammary gland.
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ABSTRACT: Ovariectomized virgin Ccnd1-/- and Ccnd1+/+ mice (5 weeks of age) were allowed to recuperate for 2 weeks. The mice were assigned to either replacement pellets containing E2 (0.75 mg, 60-day release) or pellet containing placebo. Mice were sacrificed at day 7 after pellet implantation. RNA extracted from mammary glands (3 each group) was labeled and used to probe Affymetrix 430_2.0 arrays. Six separate control Ccnd1+/+ C57BL/6 were compared to six Ccnd1-/- C57BL/6 mice. 3 mice in each group treated with placebo and three mice treated with E2
ORGANISM(S): Mus musculus
SUBMITTER: Mathew Casimiro
PROVIDER: E-GEOD-48884 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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