Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Laura Camacho
PROVIDER: E-GEOD-48934 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Camacho Laura L Guerrero Paola P Marchetti Dario D
PloS one 20130916 9
Exosomes are small membrane vesicles released by most cell types including tumor cells. The intercellular exchange of proteins and genetic material via exosomes is a potentially effective approach for cell-to-cell communication and it may perform multiple functions aiding to tumor survival and metastasis. We investigated microRNA and protein profiles of brain metastatic (BM) versus non-brain metastatic (non-BM) cell-derived exosomes. We studied the cargo of exosomes isolated from brain-tropic 70 ...[more]