Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Lars Verschuren
PROVIDER: E-GEOD-48977 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
BMC medical genomics 20140617
<h4>Background</h4>Cardiac pathological hypertrophy is associated with a significantly increased risk of coronary heart disease and has been observed in diabetic patients treated with rosiglitazone whereas most published studies do not suggest a similar increase in risk of cardiovascular events in pioglitazone-treated diabetic subjects. This study sought to understand the pathophysiological and molecular mechanisms underlying the disparate cardiovascular effects of rosiglitazone and pioglitazone ...[more]