Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Nils Blüthgen
PROVIDER: E-GEOD-49030 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hermey Guido G Mahlke Claudia C Gutzmann Jakob J JJ Schreiber Jörg J Blüthgen Nils N Kuhl Dietmar D
PloS one 20131017 10
Activity-dependent gene expression is central for sculpting neuronal connectivity in the brain. Despite the importance for synaptic plasticity, a comprehensive analysis of the temporal changes in the transcriptomic response to neuronal activity is lacking. In a genome wide survey we identified genes that were induced at 1, 4, 8, or 24 hours following neuronal activity in the hippocampus. According to their distinct expression kinetics we assigned these genes to five clusters, each containing app ...[more]