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Gene expression profiling in TPC1 cell line treated with the RTK inhibitor RPI-1

ABSTRACT: We treated the papillary thyroid carcinoma-derived cell line TPC1 with the RTK inhibitor RPI-1 to obtain a thyroid carcinoma cell model. The RET tyrosine kinase is a target of the inhibitor. Gene expression changes were evaluated comparing cells treated with the inhibitor for 24 hours versus cells treated with DMSO for 24 hours. Biological triplicates for RPI-1 and DMSO treated cells were generated by independent treatments and total RNA extractions.

ORGANISM(S): Homo sapiens

SUBMITTER: Matteo Dugo

PROVIDER: E-GEOD-49414 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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