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A Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women (MicroRNA Profiling)

ABSTRACT: The goal of this study is to identify aging-related biomarkers to improve our understanding of complex physiological changes, thereby providing a means to investigate the mechanism by which aging influences various diseases. Global microRNA expression patterns from peripheral blood of two groups of healthy young adult women, among which 13 were aged 22-25 and 9 were aged 36-39 years old, were compared to determine changes in microRNA expression that are associated with aging.

ORGANISM(S): Homo sapiens

SUBMITTER: Samantha Gadd 

PROVIDER: E-GEOD-49837 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A Parallel Study of mRNA and microRNA Profiling of Peripheral Blood in Young Adult Women.

Sredni Simone T ST   Gadd Samantha S   Jafari Nadereh N   Huang Chiang-Ching CC  

Frontiers in genetics 20110718

<h4>Background</h4>Aging is a complex process that involves the interplay of genetic, epigenetic, and environmental factors. Identifying aging-related biomarkers holds great potential for improving our understanding of complex physiological changes, thereby providing a means to investigate the mechanism by which aging influences various diseases.<h4>Method and results</h4>We performed a parallel study of microRNA and gene expression profiling of peripheral blood in a group of healthy young adult  ...[more]

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