Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Charles Warden
PROVIDER: E-GEOD-49892 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
PloS one 20131015 10
<h4>Background</h4>Pre-exposure chemoprophylaxis (PrECP) using antiretroviral agents is a promising strategy for the prevention of sexual HIV transmission in women. Molecular transporters in the human vaginal tract (VT) may play a pivotal role in determining drug disposition and, consequently, pharmacodynamic outcomes in these efforts. Little is known, however, on the expression of these transporters in vaginal tissues, representing a critical knowledge gap.<h4>Methodology/principal findings</h4 ...[more]