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Comparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth

ABSTRACT: There are histological and functional differences between human deciduous and permanent pediodontal ligament (PDL) tissues. The purpose of this study was to determine the differences between these two types of tissue at the molecular level by comparative gene expression analysis. PDL samples were obtained from permanent premolars (n=38) and anterior deciduous teeth (n=31) extracted from 40 healthy persons. Comparative cDNA microarrary analysis revealed several differences in gene expression between the deciduous and permanent PDL tissues.

ORGANISM(S): Homo sapiens

SUBMITTER: Seong-Oh Kim

PROVIDER: E-GEOD-50640 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth.

Song Je Seon JS Hwang Dong Hwan DH Kim Seong-Oh SO Jeon Mijeong M Choi Byung-Jai BJ Jung Han-Sung HS Jung Han-Sung HS Moon Seok Jun SJ Park Wonse W Choi Hyung-Jun HJ

PloS one 20130408 4

There are histological and functional differences between human deciduous and permanent periodontal ligament (PDL) tissues. The aim of this study was to determine the differences between these two types of tissue at the molecular level by comparing their gene expression patterns. PDL samples were obtained from permanent premolars (n = 38) and anterior deciduous teeth (n = 31) extracted from 40 healthy persons. Comparative cDNA microarray analysis revealed several differences in gene expression b ...[more]

PMID: 23593441

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